Publications

Schrader KA, Stratton KL, Murali R, Laitman Y, Cavallone L, Offit L, Wen YHannah, Thomas T, Shah S, Rau-Murthy R et al..  2016.  Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.. J Clin Oncol. 34(8):e61-7.

Goc J, Hepworth MR, Sonnenberg GF.  2016.  Group 3 innate lymphoid cells: regulating host-commensal bacteria interactions in inflammation and cancer.. Int Immunol. 28(1):43-52.

Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR et al..  2016.  Immunological Consequences of Intestinal Fungal Dysbiosis.. Cell Host Microbe. 19(6):865-73.

Klose CSN, Artis D.  2016.  Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis.. Nat Immunol. 17(7):765-74.

Fernandez-Ruiz D, Ng WYi, Holz LE, Ma JZ, Zaid A, Wong YChun, Lau LShong, Mollard V, Cozijnsen A, Collins N et al..  2016.  Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.. Immunity. 45(4):889-902.

Wang L, Bu P, Ai Y, Srinivasan T, Chen HJoyce, Xiang K, Lipkin SM, Shen X.  2016.  A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.. Elife. 5

Fung TC, Bessman NJ, Hepworth MR, Kumar N, Shibata N, Kobuley D, Wang K, Ziegler CGK, Goc J, Shima T et al..  2016.  Lymphoid-Tissue-Resident Commensal Bacteria Promote Members of the IL-10 Cytokine Family to Establish Mutualism.. Immunity. 44(3):634-46.

Bu P, Wang L, Chen K-Y, Srinivasan T, Murthy PKadur Laks, Tung K-L, Varanko AKristine, Chen HJoyce, Ai Y, King S et al..  2016.  A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.. Cell Stem Cell. 18(2):189-202.

Srinivasan T, Walters J, Bu P, Than EBich, Tung K-L, Chen K-Y, Panarelli N, Milsom J, Augenlicht L, Lipkin SM et al..  2016.  NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.. Cancer Res. 76(11):3411-21.

Srinivasan T, Than EBich, Bu P, Tung K-L, Chen K-Y, Augenlicht L, Lipkin SM, Shen X.  2016.  Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.. Sci Rep. 6:26069.

Kivolowitz C, Abdulhamid A, Victorio D, Castellanos J, Simpson K, Scherl E, Longman RS.  2016.  O-006 Expansion of Immunologically-Relevant E. Coli in the Intestinal Microbiota of Patients with IBD-Associated Spondyloarthritis Promotes Mucosal RORgt-Dependent Immunity.. Inflamm Bowel Dis. 22 Suppl 1:S3.

Goodenberger MKL, Thomas BC, Riegert-Johnson D, C Boland R, Plon SE, Clendenning M, Win AKo, Senter L, Lipkin SM, Stadler ZK et al..  2016.  PMS2 monoallelic mutation carriers: the known unknown.. Genet Med. 18(1):13-9.

Chen HJoyce, Wei Z, Sun J, Bhattacharya A, Savage DJ, Serda R, Mackeyev Y, Curley SA, Bu P, Wang L et al..  2016.  A recellularized human colon model identifies cancer driver genes.. Nat Biotechnol. 34(8):845-51.

Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S et al..  2016.  A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer.. Cancer Discov. 6(11):1267-1275.

Collins N, Jiang X, Zaid A, Macleod BL, Li J, Park COok, Haque A, Bedoui S, Heath WR, Mueller SN et al..  2016.  Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation.. Nat Commun. 7:11514.

Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, A Walland C, Yeiser JR, Cassis L, Carrillo J et al..  2016.  The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells.. J Exp Med. 213(10):2167-85.

Sonnenberg GF.  2016.  Transcriptionally defining ILC heterogeneity in humans.. Nat Immunol. 17(4):351-2.

Withers DR, Hepworth MR, Wang X, Mackley EC, Halford EE, Dutton EE, Marriott CL, Brucklacher-Waldert V, Veldhoen M, Kelsen J et al..  2016.  Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells.. Nat Med. 22(3):319-23.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2016.  Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 12(6):e1005684.

Robson ME, Bradbury AR, Arun B, Domchek SM, Ford JM, Hampel HL, Lipkin SM, Syngal S, Wollins DS, Lindor NM.  2015.  American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility.. J Clin Oncol. 33(31):3660-7.

Artis D, Spits H.  2015.  The biology of innate lymphoid cells.. Nature. 517(7534):293-301.

Mackley EC, Houston S, Marriott CL, Halford EE, Lucas B, Cerovic V, Filbey KJ, Maizels RM, Hepworth MR, Sonnenberg GF et al..  2015.  CCR7-dependent trafficking of RORγ⁺ ILCs creates a unique microenvironment within mucosal draining lymph nodes.. Nat Commun. 6:5862.

Chen HJoyce, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J et al..  2015.  Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.. Nat Biotechnol. 33(6):656-60.

Iliev ID.  2015.  Dectin-1 Exerts Dual Control in the Gut.. Cell Host Microbe. 18(2):139-41.

Seehus CR, Aliahmad P, de la Torre B, Iliev ID, Spurka L, Funari VA, Kaye J.  2015.  The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. Nat Immunol. 16(6):599-608.