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H
Lencz T
,
Yu J
,
Palmer C
,
Carmi S
,
Ben-Avraham D
,
Barzilai N
,
Bressman S
,
Darvasi A
,
Cho JH
,
Clark LN
,
Gümüş ZH
,
Joseph V
,
Klein R
,
Lipkin S
,
Offit K
,
Ostrer H
,
Ozelius LJ
,
Peter I
,
Atzmon G
,
Pe'er I
.
High-depth whole genome sequencing of an Ashkenazi Jewish reference panel: enhancing sensitivity, accuracy, and imputation.
Hum Genet. 2018;137(4):343-355.
Cai T
,
Cai W
,
Zhang J
,
Zheng H
,
Tsou AM
,
Xiao L
,
Zhong Z
,
Zhu J
.
Host legume-exuded antimetabolites optimize the symbiotic rhizosphere.
Mol Microbiol. 2009;73(3):507-17.
Grigg JB
,
Sonnenberg GF
.
Host-Microbiota Interactions Shape Local and Systemic Inflammatory Diseases.
J Immunol. 2017;198(2):564-571.
Doron I
,
Leonardi I
,
Li XV
,
Fiers WD
,
Semon A
,
Bialt-DeCelie M
,
Migaud M
,
Gao IH
,
Lin W-Y
,
Kusakabe T
,
Puel A
,
Iliev ID
.
Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies.
Cell. 2021;.
Preite S
,
Cannons JL
,
Radtke AJ
,
Vujkovic-Cvijin I
,
Gomez-Rodriguez J
,
Volpi S
,
Huang B
,
Cheng J
,
Collins N
,
Reilley J
,
Handon R
,
Dobbs K
,
Huq L
,
Raman I
,
Zhu C
,
Li Q-Z
,
Li MO
,
Pittaluga S
,
Uzel G
,
Notarangelo LD
,
Belkaid Y
,
Germain RN
,
Schwartzberg PL
.
Hyperactivated PI3Kδ promotes self and commensal reactivity at the expense of optimal humoral immunity.
Nat Immunol. 2018;19(9):986-1000.
I
Viladomiu M
,
Kivolowitz C
,
Abdulhamid A
,
Dogan B
,
Victorio D
,
Castellanos JG
,
Woo V
,
Teng F
,
Tran NL
,
Sczesnak A
,
Chai C
,
Kim M
,
Diehl GE
,
Ajami NJ
,
Petrosino JF
,
Zhou XK
,
Schwartzman S
,
Mandl LA
,
Abramowitz M
,
Jacob V
,
Bosworth B
,
Steinlauf A
,
Scherl EJ
,
Wu H-JJoyce
,
Simpson KW
,
Longman RS
.
IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.
Sci Transl Med. 2017;9(376).
Göktuna SI
,
Canli O
,
Bollrath J
,
Fingerle AA
,
Horst D
,
Diamanti MA
,
Pallangyo C
,
Bennecke M
,
Nebelsiek T
,
Mankan AK
,
Lang R
,
Artis D
,
Hu Y
,
Patzelt T
,
Ruland J
,
Kirchner T
,
M Taketo M
,
Chariot A
,
Arkan MC
,
Greten FR
.
IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells.
Cell Rep. 2022;38(9):110471.
Chen L
,
He Z
,
Slinger E
,
Bongers G
,
T Lapenda L
,
Pacer ME
,
Jiao J
,
Beltrao MF
,
Soto AJ
,
Harpaz N
,
Gordon RE
,
Ochando JC
,
Oukka M
,
Iuga AC
,
Chensue SW
,
Blander JM
,
Furtado GC
,
Lira SA
.
IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.
Mucosal Immunol. 2015;8(2):390-402.
Monticelli LA
,
Osborne LC
,
Noti M
,
Tran SV
,
Zaiss DMW
,
Artis D
.
IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions.
Proc Natl Acad Sci U S A. 2015;112(34):10762-7.
Topczewska PM
,
Rompe ZA
,
Jakob MO
,
Stamm A
,
Leclère PS
,
Preußer A
,
Duerr CU
,
Thole LMarie Laur
,
Kotsch K
,
Artis D
,
Klose CSN
.
ILC2 require cell-intrinsic ST2 signals to promote type 2 immune responses.
Front Immunol. 2023;14:1130933.
Lyu M
,
Suzuki H
,
Kang L
,
Gaspal F
,
Zhou W
,
Goc J
,
Zhou L
,
Zhou J
,
Zhang W
,
Shen Z
,
Fox JG
,
Sockolow RE
,
Laufer TM
,
Fan Y
,
Eberl G
,
Withers DR
,
Sonnenberg GF
.
ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut.
Nature. 2022;.
Willis JA
,
Reyes-Uribe L
,
Chang K
,
Lipkin SM
,
Vilar E
.
Immune Activation in Mismatch Repair-Deficient Carcinogenesis: More Than Just Mutational Rate.
Clin Cancer Res. 2020;26(1):11-17.
Li XV
,
Leonardi I
,
Putzel GG
,
Semon A
,
Fiers WD
,
Kusakabe T
,
Lin W-Y
,
Gao IH
,
Doron I
,
Gutierrez-Guerrero A
,
DeCelie MB
,
Carriche GM
,
Mesko M
,
Yang C
,
Naglik JR
,
Hube B
,
Scherl EJ
,
Iliev ID
.
Immune regulation by fungal strain diversity in inflammatory bowel disease.
Nature. 2022;603(7902):672-678.
Brestoff JR
,
Artis D
.
Immune regulation of metabolic homeostasis in health and disease.
Cell. 2015;161(1):146-60.
Hepworth MR
,
Fung TC
,
Masur SH
,
Kelsen JR
,
McConnell FM
,
Dubrot J
,
Withers DR
,
Hugues S
,
Farrar MA
,
Reith W
,
Eberl G
,
Baldassano RN
,
Laufer TM
,
Elson CO
,
Sonnenberg GF
.
Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.
Science. 2015;348(6238):1031-5.
Lionakis MS
,
Iliev ID
,
Hohl TM
.
Immunity against fungi.
JCI Insight. 2017;2(11).
Doron I
,
Kusakabe T
,
Iliev ID
.
Immunoglobulins at the interface of the gut mycobiota and anti-fungal immunity.
Semin Immunol. 2023;67:101757.
Wheeler ML
,
Limon JJ
,
Bar AS
,
Leal CA
,
Gargus M
,
Tang J
,
Brown J
,
Funari VA
,
Wang HL
,
Crother TR
,
Arditi M
,
Underhill DM
,
Iliev ID
.
Immunological Consequences of Intestinal Fungal Dysbiosis.
Cell Host Microbe. 2016;19(6):865-73.
Rajan A
,
Pan Y
,
Mahtani P
,
Niec R
,
Longman R
,
Gerber J
,
Lukin D
,
Scherl E
,
Battat R
.
The Impact of Confounders on Symptom-Endoscopic Discordances in Crohn's Disease.
Crohns Colitis 360. 2023;5(2):otad017.
Zhou L
,
Sonnenberg GF
.
In Situ Support of ILC Precursors.
Immunity. 2020;52(2):207-209.
Moretti J
,
J Blander M
.
Increasing complexity of NLRP3 inflammasome regulation.
J Leukoc Biol. 2020;.
Porras AMaria
,
Zhou H
,
Shi Q
,
Xiao X
,
Longman R
,
Brito ILauren
.
Inflammatory Bowel Disease-Associated Gut Commensals Degrade Components of the Extracellular Matrix.
mBio. 2022;13(6):e0220122.
Awasthi D
,
Chopra S
,
Cho BA
,
Emmanuelli A
,
Sandoval TA
,
Hwang S-M
,
Chae C-S
,
Salvagno C
,
Tan C
,
Vasquez-Urbina L
,
Rodriguez JJFernande
,
Santagostino SF
,
Iwawaki T
,
E Romero-Sandoval A
,
Crespo MSanchez
,
Morales DK
,
Iliev ID
,
Hohl TM
,
Cubillos-Ruiz JR
.
Inflammatory ER stress responses dictate the immunopathogenic progression of systemic candidiasis.
J Clin Invest. 2023;133(17).
Jahid S
,
Sun J
,
Gelincik O
,
Blecua P
,
Edelmann W
,
Kucherlapati R
,
Zhou K
,
Jasin M
,
Gümüş ZH
,
Lipkin SM
.
Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.
Oncotarget. 2017;8(42):71574-71586.
Torchinsky MBeer
,
Garaude J
,
Martin AP
,
J Blander M
.
Innate immune recognition of infected apoptotic cells directs T(H)17 cell differentiation.
Nature. 2009;458(7234):78-82.
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