Submitted by jec3011 on March 6, 2020 - 12:00pm
Title | In Situ Support of ILC Precursors. |
Publication Type | Journal Article |
Year of Publication | 2020 |
Authors | Zhou, L, Sonnenberg, GF |
Journal | Immunity |
Volume | 52 |
Issue | 2 |
Pagination | 207-209 |
Date Published | 2020 Feb 18 |
ISSN | 1097-4180 |
Abstract | Innate lymphoid cells (ILCs) are tissue-resident lymphocytes that promote immunity to pathogens at mucosal barriers, but the mechanisms regulating their development within tissues remain poorly understood. In this issue of Immunity, Oherle et al. identify a niche in the neonatal airway where stromal cell-derived insulin-like growth factor 1 (IGF1) supports the proliferation of ILC precursors and protects from infection. |
DOI | 10.1016/j.immuni.2020.01.011 |
Alternate Journal | Immunity |
PubMed ID | 32075721 |