Publications

Zaiss DMW, Gause WC, Osborne LC, Artis D.  2015.  Emerging functions of amphiregulin in orchestrating immunity, inflammation, and tissue repair.. Immunity. 42(2):216-26.

Giacomin PR, Moy RH, Noti M, Osborne LC, Siracusa MC, Alenghat T, Liu B, McCorkell KA, Troy AE, Rak GD et al..  2015.  Epithelial-intrinsic IKKα expression regulates group 3 innate lymphoid cell responses and antibacterial immunity.. J Exp Med. 212(10):1513-28.

Kelsen JR, Dawany N, Moran CJ, Petersen B-S, Sarmady M, Sasson A, Pauly-Hubbard H, Martinez A, Maurer K, Soong J et al..  2015.  Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.. Gastroenterology. 149(6):1415-24.

Longman RS, Littman DR.  2015.  The functional impact of the intestinal microbiome on mucosal immunity and systemic autoimmunity.. Curr Opin Rheumatol. 27(4):381-7.

Topka S, Vijai J, Walsh MF, Jacobs L, Maria A, Villano D, Gaddam P, Wu G, McGee RB, Quinn E et al..  2015.  Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.. PLoS Genet. 11(6):e1005262.

Bergstrom KSB, Morampudi V, Chan JM, Bhinder G, Lau J, Yang H, Ma C, Huang T, Ryz N, Sham HPan et al..  2015.  Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.. PLoS Pathog. 11(8):e1005108.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al..  2015.  Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.

Wagage S, Pritchard GHarms, Dawson L, Buza EL, Sonnenberg GF, Hunter CA.  2015.  The Group 3 Innate Lymphoid Cell Defect in Aryl Hydrocarbon Receptor Deficient Mice Is Associated with T Cell Hyperactivation during Intestinal Infection.. PLoS One. 10(5):e0128335.

Chen L, He Z, Slinger E, Bongers G, T Lapenda L, Pacer ME, Jiao J, Beltrao MF, Soto AJ, Harpaz N et al..  2015.  IL-23 activates innate lymphoid cells to promote neonatal intestinal pathology.. Mucosal Immunol. 8(2):390-402.

Monticelli LA, Osborne LC, Noti M, Tran SV, Zaiss DMW, Artis D.  2015.  IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions.. Proc Natl Acad Sci U S A. 112(34):10762-7.

Brestoff JR, Artis D.  2015.  Immune regulation of metabolic homeostasis in health and disease.. Cell. 161(1):146-60.

Hepworth MR, Fung TC, Masur SH, Kelsen JR, McConnell FM, Dubrot J, Withers DR, Hugues S, Farrar MA, Reith W et al..  2015.  Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.. Science. 348(6238):1031-5.

Sonnenberg GF, Artis D.  2015.  Innate lymphoid cells in the initiation, regulation and resolution of inflammation.. Nat Med. 21(7):698-708.

Kelsen JR, Baldassano RN, Artis D, Sonnenberg GF.  2015.  Maintaining intestinal health: the genetics and immunology of very early onset inflammatory bowel disease.. Cell Mol Gastroenterol Hepatol. 1(5):462-476.

Bu P, Wang L, Chen K-Y, Rakhilin N, Sun J, Closa A, Tung K-L, King S, Varanko AKristine, Xu Y et al..  2015.  miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.. Nat Commun. 6:6879.

Tang J, Iliev ID, Brown J, Underhill DM, Funari VA.  2015.  Mycobiome: Approaches to analysis of intestinal fungi.. J Immunol Methods. 421:112-21.

Gillen DL, Meyskens FL, Morgan TR, Zell JA, Carroll R, Benya R, Chen W-P, Mo A, Tucker C, Bhattacharya A et al..  2015.  A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectum.. Cancer Prev Res (Phila). 8(3):222-30.

Müller S, Wolf AJ, Iliev ID, Berg BL, Underhill DM, Liu GY.  2015.  Poorly Cross-Linked Peptidoglycan in MRSA Due to mecA Induction Activates the Inflammasome and Exacerbates Immunopathology.. Cell Host Microbe. 18(5):604-12.

Hirten R, Longman RS, Bosworth BP, Steinlauf A, Scherl E.  2015.  Vedolizumab and Infliximab Combination Therapy in the Treatment of Crohn's Disease.. Am J Gastroenterol. 110(12):1737-8.

Rimmelé P, Bigarella CL, Liang R, Izac B, Dieguez-Gonzalez R, Barbet G, Donovan M, Brugnara C, Blander JM, Sinclair DA et al..  2014.  Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells.. Stem Cell Reports. 3(1):44-59.

Fung TC, Artis D, Sonnenberg GF.  2014.  Anatomical localization of commensal bacteria in immune cell homeostasis and disease.. Immunol Rev. 260(1):35-49.

Motomura Y, Morita H, Moro K, Nakae S, Artis D, Endo TA, Kuroki Y, Ohara O, Koyasu S, Kubo M.  2014.  Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation.. Immunity. 40(5):758-71.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF et al..  2014.  A central role for Notch in effector CD8(+) T cell differentiation.. Nat Immunol. 15(12):1143-51.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al..  2014.  Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Longman RS, Diehl GE, Victorio DA, Huh JR, Galan C, Miraldi ER, Swaminath A, Bonneau R, Scherl EJ, Littman DR.  2014.  CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.. J Exp Med. 211(8):1571-83.