Publications

Kelsen JR, Dawany N, Moran CJ, Petersen B-S, Sarmady M, Sasson A, Pauly-Hubbard H, Martinez A, Maurer K, Soong J et al..  2015.  Exome sequencing analysis reveals variants in primary immunodeficiency genes in patients with very early onset inflammatory bowel disease.. Gastroenterology. 149(6):1415-24.

Bergstrom KSB, Morampudi V, Chan JM, Bhinder G, Lau J, Yang H, Ma C, Huang T, Ryz N, Sham HPan et al..  2015.  Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.. PLoS Pathog. 11(8):e1005108.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al..  2015.  Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.

Monticelli LA, Osborne LC, Noti M, Tran SV, Zaiss DMW, Artis D.  2015.  IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions.. Proc Natl Acad Sci U S A. 112(34):10762-7.

Brestoff JR, Artis D.  2015.  Immune regulation of metabolic homeostasis in health and disease.. Cell. 161(1):146-60.

Sonnenberg GF, Artis D.  2015.  Innate lymphoid cells in the initiation, regulation and resolution of inflammation.. Nat Med. 21(7):698-708.

Kelsen JR, Baldassano RN, Artis D, Sonnenberg GF.  2015.  Maintaining intestinal health: the genetics and immunology of very early onset inflammatory bowel disease.. Cell Mol Gastroenterol Hepatol. 1(5):462-476.

Gillen DL, Meyskens FL, Morgan TR, Zell JA, Carroll R, Benya R, Chen W-P, Mo A, Tucker C, Bhattacharya A et al..  2015.  A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectum.. Cancer Prev Res (Phila). 8(3):222-30.

Mahlakõiv T, Artis D.  2016.  Allergen Exposure: When Timing Is Everything.. Immunity. 45(6):1188-1190.

Monticelli LA, Buck MD, Flamar A-L, Saenz SA, Wojno EDTait, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald H-R et al..  2016.  Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.. Nat Immunol. 17(6):656-65.

Legarda D, Justus SJ, Ang RL, Rikhi N, Li W, Moran TM, Zhang J, Mizoguchi E, Zelic M, Kelliher MA et al..  2016.  CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.. Cell Rep. 15(11):2449-61.

Wojno EDTait, Artis D.  2016.  Emerging concepts and future challenges in innate lymphoid cell biology.. J Exp Med. 213(11):2229-2248.

Schrader KA, Stratton KL, Murali R, Laitman Y, Cavallone L, Offit L, Wen YHannah, Thomas T, Shah S, Rau-Murthy R et al..  2016.  Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.. J Clin Oncol. 34(8):e61-7.

Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR et al..  2016.  Immunological Consequences of Intestinal Fungal Dysbiosis.. Cell Host Microbe. 19(6):865-73.

Klose CSN, Artis D.  2016.  Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis.. Nat Immunol. 17(7):765-74.

Wang L, Bu P, Ai Y, Srinivasan T, Chen HJoyce, Xiang K, Lipkin SM, Shen X.  2016.  A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.. Elife. 5

Bu P, Wang L, Chen K-Y, Srinivasan T, Murthy PKadur Laks, Tung K-L, Varanko AKristine, Chen HJoyce, Ai Y, King S et al..  2016.  A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.. Cell Stem Cell. 18(2):189-202.

Srinivasan T, Walters J, Bu P, Than EBich, Tung K-L, Chen K-Y, Panarelli N, Milsom J, Augenlicht L, Lipkin SM et al..  2016.  NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.. Cancer Res. 76(11):3411-21.

Srinivasan T, Than EBich, Bu P, Tung K-L, Chen K-Y, Augenlicht L, Lipkin SM, Shen X.  2016.  Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.. Sci Rep. 6:26069.

Kivolowitz C, Abdulhamid A, Victorio D, Castellanos J, Simpson K, Scherl E, Longman RS.  2016.  O-006 Expansion of Immunologically-Relevant E. Coli in the Intestinal Microbiota of Patients with IBD-Associated Spondyloarthritis Promotes Mucosal RORgt-Dependent Immunity.. Inflamm Bowel Dis. 22 Suppl 1:S3.

Goodenberger MKL, Thomas BC, Riegert-Johnson D, C Boland R, Plon SE, Clendenning M, Win AKo, Senter L, Lipkin SM, Stadler ZK et al..  2016.  PMS2 monoallelic mutation carriers: the known unknown.. Genet Med. 18(1):13-9.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2016.  Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 12(6):e1005684.

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2017.  Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 23(7):878-884.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2017.  Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 13(2):e1006223.

Viladomiu M, Kivolowitz C, Abdulhamid A, Dogan B, Victorio D, Castellanos JG, Woo V, Teng F, Tran NL, Sczesnak A et al..  2017.  IgA-coated E. coli enriched in Crohn's disease spondyloarthritis promote TH17-dependent inflammation.. Sci Transl Med. 9(376)