Publications

Sei S, Ahadova A, Keskin DB, Bohaumilitzky L, Gebert J, Doeberitz Mvon Knebel, Lipkin SM, Kloor M.  2023.  Lynch syndrome cancer vaccines: A roadmap for the development of precision immunoprevention strategies.. Front Oncol. 13:1147590.

Offit K, Sharkey CM, Green D, Wu X, Trottier M, Hamilton JG, Walsh MF, Dandiker S, Belhadj S, Lipkin SM et al..  2023.  Regulation of Laboratory-Developed Tests in Preventive Oncology: Emerging Needs and Opportunities.. J Clin Oncol. 41(1):11-21.

Viladomiu M, Khounlotham M, Dogan B, Lima SF, Elsaadi A, Cardakli E, Castellanos JG, Ng C, Herzog J, Schoenborn AA et al..  2022.  Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis.. Cell Rep. 41(7):111637.

Dohlman AB, Mendoza DArguijo, Ding S, Gao M, Dressman H, Iliev ID, Lipkin SM, Shen X.  2020.  The cancer microbiome atlas: a pan-cancer comparative analysis to distinguish tissue-resident microbiota from contaminants.. Cell Host Microbe.

Offit K, Tkachuk KA, Stadler ZK, Walsh MF, Diaz-Zabala H, Levin JD, Steinsnyder Z, Ravichandran V, Sharaf RN, Frey MK et al..  2020.  Cascading After Peridiagnostic Cancer Genetic Testing: An Alternative to Population-Based Screening.. J Clin Oncol. :JCO1902010.

Willis JA, Reyes-Uribe L, Chang K, Lipkin SM, Vilar E.  2020.  Immune Activation in Mismatch Repair-Deficient Carcinogenesis: More Than Just Mutational Rate.. Clin Cancer Res. 26(1):11-17.

Artomov M, Joseph V, Tiao G, Thomas T, Schrader K, Klein RJ, Kiezun A, Gupta N, Margolin L, Stratigos AJ et al..  2019.  Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes.. Eur J Hum Genet. 27(5):824-828.

Pertesi M, Vallée M, Wei X, Revuelta MV, Galia P, Demangel D, Oliver J, Foll M, Chen S, Perrial E et al..  2019.  Exome sequencing identifies germline variants in DIS3 in familial multiple myeloma.. Leukemia. 33(9):2324-2330.

Huang S-H, McCann CD, Mota TM, Wang C, Lipkin SM, R Jones B.  2019.  Have Cells Harboring the HIV Reservoir Been Immunoedited? Front Immunol. 10:1842.

Liu J, Hsieh C-L, Gelincik O, Devolder B, Sei S, Zhang S, Lipkin SM, Chang Y-F.  2019.  Proteomic characterization of outer membrane vesicles from gut mucosa-derived fusobacterium nucleatum.. J Proteomics. 195:125-137.

Wei X, M Calvo-Vidal N, Chen S, Wu G, Revuelta MV, Sun J, Zhang J, Walsh MF, Nichols KE, Joseph V et al..  2018.  Germline Lysine-Specific Demethylase 1 () Mutations Confer Susceptibility to Multiple Myeloma.. Cancer Res. 78(10):2747-2759.

Choi J, Rakhilin N, Gadamsetty P, Joe DJ, Tabrizian T, Lipkin SM, Huffman DM, Shen X, Nishimura N.  2018.  Intestinal crypts recover rapidly from focal damage with coordinated motion of stem cells that is impaired by aging.. Sci Rep. 8(1):10989.

Waller RG, Darlington TM, Wei X, Madsen MJ, Thomas A, Curtin K, Coon H, Rajamanickam V, Musinsky J, Jayabalan D et al..  2018.  Novel pedigree analysis implicates DNA repair and chromatin remodeling in multiple myeloma risk.. PLoS Genet. 14(2):e1007111.

Chen K-Y, Srinivasan T, Lin C, Tung K-L, Gao Z, Hsu DS, Lipkin SM, Shen X.  2018.  Single-Cell Transcriptomics Reveals Heterogeneity and Drug Response of Human Colorectal Cancer Organoids.. Conf Proc IEEE Eng Med Biol Soc. 2018:2378-2381.

Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM.  2017.  Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.. Oncotarget. 8(42):71574-71586.

Mandelker D, Zhang L, Kemel Y, Stadler ZK, Joseph V, Zehir A, Pradhan N, Arnold A, Walsh MF, Li Y et al..  2017.  Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing.. JAMA. 318(9):825-835.

Chen K-Y, Srinivasan T, Tung K-L, Belmonte JM, Wang L, Murthy PKadur Laks, Choi J, Rakhilin N, King S, Varanko AKristine et al..  2017.  A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.. Mol Syst Biol. 13(4):927.

Schrader KA, Stratton KL, Murali R, Laitman Y, Cavallone L, Offit L, Wen YHannah, Thomas T, Shah S, Rau-Murthy R et al..  2016.  Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.. J Clin Oncol. 34(8):e61-7.

Wang L, Bu P, Ai Y, Srinivasan T, Chen HJoyce, Xiang K, Lipkin SM, Shen X.  2016.  A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.. Elife. 5

Bu P, Wang L, Chen K-Y, Srinivasan T, Murthy PKadur Laks, Tung K-L, Varanko AKristine, Chen HJoyce, Ai Y, King S et al..  2016.  A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.. Cell Stem Cell. 18(2):189-202.

Srinivasan T, Walters J, Bu P, Than EBich, Tung K-L, Chen K-Y, Panarelli N, Milsom J, Augenlicht L, Lipkin SM et al..  2016.  NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.. Cancer Res. 76(11):3411-21.

Srinivasan T, Than EBich, Bu P, Tung K-L, Chen K-Y, Augenlicht L, Lipkin SM, Shen X.  2016.  Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.. Sci Rep. 6:26069.

Goodenberger MKL, Thomas BC, Riegert-Johnson D, C Boland R, Plon SE, Clendenning M, Win AKo, Senter L, Lipkin SM, Stadler ZK et al..  2016.  PMS2 monoallelic mutation carriers: the known unknown.. Genet Med. 18(1):13-9.

Chen HJoyce, Wei Z, Sun J, Bhattacharya A, Savage DJ, Serda R, Mackeyev Y, Curley SA, Bu P, Wang L et al..  2016.  A recellularized human colon model identifies cancer driver genes.. Nat Biotechnol. 34(8):845-51.

Robson ME, Bradbury AR, Arun B, Domchek SM, Ford JM, Hampel HL, Lipkin SM, Syngal S, Wollins DS, Lindor NM.  2015.  American Society of Clinical Oncology Policy Statement Update: Genetic and Genomic Testing for Cancer Susceptibility.. J Clin Oncol. 33(31):3660-7.