Publications

Blander JM, Visintin I, Janeway CA, Medzhitov R.  1999.  Alpha(1,3)-fucosyltransferase VII and alpha(2,3)-sialyltransferase IV are up-regulated in activated CD4 T cells and maintained after their differentiation into Th1 and migration into inflammatory sites.. J Immunol. 163(7):3746-52.

Garaude J, Kent A, van Rooijen N, J Blander M.  2012.  Simultaneous targeting of toll- and nod-like receptors induces effective tumor-specific immune responses.. Sci Transl Med. 4(120):120ra16.

Mackay LK, Rahimpour A, Ma JZ, Collins N, Stock AT, Hafon M-L, Vega-Ramos J, Lauzurica P, Mueller SN, Stefanovic T et al..  2013.  The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.. Nat Immunol. 14(12):1294-301.

Shan M, Gentile M, Yeiser JR, A Walland C, Bornstein VU, Chen K, He B, Cassis L, Bigas A, Cols M et al..  2013.  Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals.. Science. 342(6157):447-53.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF et al..  2014.  A central role for Notch in effector CD8(+) T cell differentiation.. Nat Immunol. 15(12):1143-51.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF et al..  2014.  A central role for Notch in effector CD8(+) T cell differentiation.. Nat Immunol. 15(12):1143-51.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF et al..  2014.  A central role for Notch in effector CD8(+) T cell differentiation.. Nat Immunol. 15(12):1143-51.

Backer RA, Helbig C, Gentek R, Kent A, Laidlaw BJ, Dominguez CX, de Souza YS, van Trierum SE, van Beek R, Rimmelzwaan GF et al..  2014.  A central role for Notch in effector CD8(+) T cell differentiation.. Nat Immunol. 15(12):1143-51.

Osborne LC, Monticelli LA, Nice TJ, Sutherland TE, Siracusa MC, Hepworth MR, Tomov VT, Kobuley D, Tran SV, Bittinger K et al..  2014.  Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.. Science. 345(6196):578-82.

Longman RS, Diehl GE, Victorio DA, Huh JR, Galan C, Miraldi ER, Swaminath A, Bonneau R, Scherl EJ, Littman DR.  2014.  CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.. J Exp Med. 211(8):1571-83.

Sawant DV, Gravano DM, Vogel P, Giacomin P, Artis D, Vignali DAA.  2014.  Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection.. J Immunol. 192(6):2904-12.

Sawant DV, Gravano DM, Vogel P, Giacomin P, Artis D, Vignali DAA.  2014.  Regulatory T cells limit induction of protective immunity and promote immune pathology following intestinal helminth infection.. J Immunol. 192(6):2904-12.

Topka S, Vijai J, Walsh MF, Jacobs L, Maria A, Villano D, Gaddam P, Wu G, McGee RB, Quinn E et al..  2015.  Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.. PLoS Genet. 11(6):e1005262.

Topka S, Vijai J, Walsh MF, Jacobs L, Maria A, Villano D, Gaddam P, Wu G, McGee RB, Quinn E et al..  2015.  Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.. PLoS Genet. 11(6):e1005262.

Bergstrom KSB, Morampudi V, Chan JM, Bhinder G, Lau J, Yang H, Ma C, Huang T, Ryz N, Sham HPan et al..  2015.  Goblet Cell Derived RELM-β Recruits CD4+ T Cells during Infectious Colitis to Promote Protective Intestinal Epithelial Cell Proliferation.. PLoS Pathog. 11(8):e1005108.

Bu P, Wang L, Chen K-Y, Rakhilin N, Sun J, Closa A, Tung K-L, King S, Varanko AKristine, Xu Y et al..  2015.  miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.. Nat Commun. 6:6879.

Schrader KA, Stratton KL, Murali R, Laitman Y, Cavallone L, Offit L, Wen YHannah, Thomas T, Shah S, Rau-Murthy R et al..  2016.  Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.. J Clin Oncol. 34(8):e61-7.

Bu P, Wang L, Chen K-Y, Srinivasan T, Murthy PKadur Laks, Tung K-L, Varanko AKristine, Chen HJoyce, Ai Y, King S et al..  2016.  A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.. Cell Stem Cell. 18(2):189-202.

Kivolowitz C, Abdulhamid A, Victorio D, Castellanos J, Simpson K, Scherl E, Longman RS.  2016.  O-006 Expansion of Immunologically-Relevant E. Coli in the Intestinal Microbiota of Patients with IBD-Associated Spondyloarthritis Promotes Mucosal RORgt-Dependent Immunity.. Inflamm Bowel Dis. 22 Suppl 1:S3.

Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S et al..  2016.  A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer.. Cancer Discov. 6(11):1267-1275.

Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S et al..  2016.  A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer.. Cancer Discov. 6(11):1267-1275.

Withers DR, Hepworth MR, Wang X, Mackley EC, Halford EE, Dutton EE, Marriott CL, Brucklacher-Waldert V, Veldhoen M, Kelsen J et al..  2016.  Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells.. Nat Med. 22(3):319-23.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2016.  Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 12(6):e1005684.

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2017.  Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 23(7):878-884.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2017.  Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 13(2):e1006223.