Publications

Ladinsky MS, Araujo LP, Zhang X, Veltri J, Galan-Diez M, Soualhi S, Lee C, Irie K, Pinker EY, Narushima S et al..  2019.  Endocytosis of commensal antigens by intestinal epithelial cells regulates mucosal T cell homeostasis.. Science. 363(6431)

Witherspoon M, Sandu D, Lu C, Wang K, Edwards R, Yeung A, Gelincik O, Manfredi G, Gross S, Kopelovich L et al..  2019.  ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer.. Oncotarget. 10(40):4004-4017.

Zhou L, Chu C, Teng F, Bessman NJ, Goc J, Santosa EK, Putzel GG, Kabata H, Kelsen JR, Baldassano RN et al..  2019.  Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2.. Nature. 568(7752):405-409.

Goettel JA, Kotlarz D, Emani R, Canavan JB, Konnikova L, Illig D, Frei SM, Field M, Kowalik M, Peng K et al..  2019.  Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model.. Cell Mol Gastroenterol Hepatol.

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2018.  Corrigendum: Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 24(4):526.

Vivier E, Artis D, Colonna M, Diefenbach A, Di Santo JP, Eberl G, Koyasu S, Locksley RM, McKenzie ANJ, Mebius RE et al..  2018.  Innate Lymphoid Cells: 10 Years On.. Cell. 174(5):1054-1066.

Park COok, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JHye et al..  2018.  Staged development of long-lived T-cell receptor αβ TH17 resident memory T-cell population to Candida albicans after skin infection.. J Allergy Clin Immunol. 142(2):647-662.

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2017.  Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 23(7):878-884.

Chen S, Beltrán JF, Esteban-Jurado C, Franch-Expósito S, Castellví-Bel S, Lipkin S, Wei X, Yu H.  2017.  GeMSTONE: orchestrated prioritization of human germline mutations in the cloud.. Nucleic Acids Res. 45(W1):W207-W214.

Jahid S, Sun J, Gelincik O, Blecua P, Edelmann W, Kucherlapati R, Zhou K, Jasin M, Gümüş ZH, Lipkin SM.  2017.  Inhibition of colorectal cancer genomic copy number alterations and chromosomal fragile site tumor suppressor FHIT and WWOX deletions by DNA mismatch repair.. Oncotarget. 8(42):71574-71586.

Campisi L, Barbet G, Ding Y, Esplugues E, Flavell RA, J Blander M.  2016.  Apoptosis in response to microbial infection induces autoreactive TH17 cells.. Nat Immunol. 17(9):1084-92.

Chen HJoyce, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J et al..  2015.  Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.. Nat Biotechnol. 33(6):656-60.

Chen HJoyce, Sun J, Huang Z, Hou H, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J et al..  2015.  Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.. Nat Biotechnol. 33(6):656-60.

Topka S, Vijai J, Walsh MF, Jacobs L, Maria A, Villano D, Gaddam P, Wu G, McGee RB, Quinn E et al..  2015.  Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.. PLoS Genet. 11(6):e1005262.

Hepworth MR, Fung TC, Masur SH, Kelsen JR, McConnell FM, Dubrot J, Withers DR, Hugues S, Farrar MA, Reith W et al..  2015.  Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.. Science. 348(6238):1031-5.

Hepworth MR, Fung TC, Masur SH, Kelsen JR, McConnell FM, Dubrot J, Withers DR, Hugues S, Farrar MA, Reith W et al..  2015.  Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells.. Science. 348(6238):1031-5.

Motomura Y, Morita H, Moro K, Nakae S, Artis D, Endo TA, Kuroki Y, Ohara O, Koyasu S, Kubo M.  2014.  Basophil-derived interleukin-4 controls the function of natural helper cells, a member of ILC2s, in lung inflammation.. Immunity. 40(5):758-71.