Publications

Topka S, Vijai J, Walsh MF, Jacobs L, Maria A, Villano D, Gaddam P, Wu G, McGee RB, Quinn E et al..  2015.  Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.. PLoS Genet. 11(6):e1005262.

Brestoff JR, Kim BS, Saenz SA, Stine RR, Monticelli LA, Sonnenberg GF, Thome JJ, Farber DL, Lutfy K, Seale P et al..  2015.  Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity.. Nature. 519(7542):242-6.

Monticelli LA, Osborne LC, Noti M, Tran SV, Zaiss DMW, Artis D.  2015.  IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin-EGFR interactions.. Proc Natl Acad Sci U S A. 112(34):10762-7.

Bu P, Wang L, Chen K-Y, Rakhilin N, Sun J, Closa A, Tung K-L, King S, Varanko AKristine, Xu Y et al..  2015.  miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.. Nat Commun. 6:6879.

Tang J, Iliev ID, Brown J, Underhill DM, Funari VA.  2015.  Mycobiome: Approaches to analysis of intestinal fungi.. J Immunol Methods. 421:112-21.

Gillen DL, Meyskens FL, Morgan TR, Zell JA, Carroll R, Benya R, Chen W-P, Mo A, Tucker C, Bhattacharya A et al..  2015.  A phase IIa randomized, double-blind trial of erlotinib in inhibiting epidermal growth factor receptor signaling in aberrant crypt foci of the colorectum.. Cancer Prev Res (Phila). 8(3):222-30.

Monticelli LA, Buck MD, Flamar A-L, Saenz SA, Wojno EDTait, Yudanin NA, Osborne LC, Hepworth MR, Tran SV, Rodewald H-R et al..  2016.  Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.. Nat Immunol. 17(6):656-65.

Legarda D, Justus SJ, Ang RL, Rikhi N, Li W, Moran TM, Zhang J, Mizoguchi E, Zelic M, Kelliher MA et al..  2016.  CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN.. Cell Rep. 15(11):2449-61.

Schrader KA, Stratton KL, Murali R, Laitman Y, Cavallone L, Offit L, Wen YHannah, Thomas T, Shah S, Rau-Murthy R et al..  2016.  Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.. J Clin Oncol. 34(8):e61-7.

Wheeler ML, Limon JJ, Bar AS, Leal CA, Gargus M, Tang J, Brown J, Funari VA, Wang HL, Crother TR et al..  2016.  Immunological Consequences of Intestinal Fungal Dysbiosis.. Cell Host Microbe. 19(6):865-73.

Fernandez-Ruiz D, Ng WYi, Holz LE, Ma JZ, Zaid A, Wong YChun, Lau LShong, Mollard V, Cozijnsen A, Collins N et al..  2016.  Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.. Immunity. 45(4):889-902.

Fernandez-Ruiz D, Ng WYi, Holz LE, Ma JZ, Zaid A, Wong YChun, Lau LShong, Mollard V, Cozijnsen A, Collins N et al..  2016.  Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.. Immunity. 45(4):889-902.

Bu P, Wang L, Chen K-Y, Srinivasan T, Murthy PKadur Laks, Tung K-L, Varanko AKristine, Chen HJoyce, Ai Y, King S et al..  2016.  A miR-34a-Numb Feedforward Loop Triggered by Inflammation Regulates Asymmetric Stem Cell Division in Intestine and Colon Cancer.. Cell Stem Cell. 18(2):189-202.

Srinivasan T, Walters J, Bu P, Than EBich, Tung K-L, Chen K-Y, Panarelli N, Milsom J, Augenlicht L, Lipkin SM et al..  2016.  NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.. Cancer Res. 76(11):3411-21.

Srinivasan T, Walters J, Bu P, Than EBich, Tung K-L, Chen K-Y, Panarelli N, Milsom J, Augenlicht L, Lipkin SM et al..  2016.  NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer-Initiating Cells.. Cancer Res. 76(11):3411-21.

Srinivasan T, Than EBich, Bu P, Tung K-L, Chen K-Y, Augenlicht L, Lipkin SM, Shen X.  2016.  Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.. Sci Rep. 6:26069.

Srinivasan T, Than EBich, Bu P, Tung K-L, Chen K-Y, Augenlicht L, Lipkin SM, Shen X.  2016.  Notch signalling regulates asymmetric division and inter-conversion between lgr5 and bmi1 expressing intestinal stem cells.. Sci Rep. 6:26069.

Goodenberger MKL, Thomas BC, Riegert-Johnson D, C Boland R, Plon SE, Clendenning M, Win AKo, Senter L, Lipkin SM, Stadler ZK et al..  2016.  PMS2 monoallelic mutation carriers: the known unknown.. Genet Med. 18(1):13-9.

Goodenberger MKL, Thomas BC, Riegert-Johnson D, C Boland R, Plon SE, Clendenning M, Win AKo, Senter L, Lipkin SM, Stadler ZK et al..  2016.  PMS2 monoallelic mutation carriers: the known unknown.. Genet Med. 18(1):13-9.

Goodenberger MKL, Thomas BC, Riegert-Johnson D, C Boland R, Plon SE, Clendenning M, Win AKo, Senter L, Lipkin SM, Stadler ZK et al..  2016.  PMS2 monoallelic mutation carriers: the known unknown.. Genet Med. 18(1):13-9.

Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S et al..  2016.  A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer.. Cancer Discov. 6(11):1267-1275.

Vijai J, Topka S, Villano D, Ravichandran V, Maxwell KN, Maria A, Thomas T, Gaddam P, Lincoln A, Kazzaz S et al..  2016.  A Recurrent ERCC3 Truncating Mutation Confers Moderate Risk for Breast Cancer.. Cancer Discov. 6(11):1267-1275.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2016.  Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 12(6):e1005684.

Crespo M, Vilar E, Tsai S-Y, Chang K, Amin S, Srinivasan T, Zhang T, Pipalia NH, Chen HJoyce, Witherspoon M et al..  2017.  Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing.. Nat Med. 23(7):878-884.

Nice TJ, Osborne LC, Tomov VT, Artis D, E Wherry J, Virgin HW.  2017.  Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity.. PLoS Pathog. 13(2):e1006223.